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Protection by cyclosporin A of mitochondrial and cellular functions during a cold preservation–warm reperfusion of rat liver

✍ Scribed by Catherine Plin; Pierre S Haddad; Jean-Paul Tillement; Aziz Elimadi; Didier Morin

Book ID
113584788
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
228 KB
Volume
495
Category
Article
ISSN
0014-2999

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Preservation of the liver involves a period of cold (0" to 4" C) ischemia; the longer the ischemic period, the greater the injury to the liver. The mechanisms for cold-induced ischemic injury are not known, but it is clear that after preservation the liver has a reduced capacity to regenerate high-e