Protection by Abana, a Herbomineral Preparation, against Myocardial Necrosis in Rats Induced by Isoproterenol

✍ Scribed by Smita Tandon; Ravi Rastogi; Narinder Kumar Kapoor

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 292 KB
• Volume: 10
• Category: Article
• ISSN: 0951-418X
• DOI: 10.1002/(sici)1099-1573(199605)10:3<263::aid-ptr814>3.0.co;2-u

✦ Synopsis

Abana, a herbomineral preparation, showed significant protection against the biochemical changes induced by isoproterenol in rats. In myocardial necrosis, the increased levels of serum creatine phosphokinase, glutamate oxaloacetate transaminase, glutamate pyruvate transaminase and y-glutamyl transpeptidase were found to be reversed by Abana treatment. In addition the decreased levels of glycogen, y-glutamyl transpeptidase, succinate dehydrogenase and mitochondrial oxygen uptake in heart were also significantly protected. This shows that Abana treatment could contribute to restoring myocardial integrity and cardiac function disturbed by isoproterenol-induced ischaemia.