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Protection against titanium particle induced osteolysis by cannabinoid receptor 2 selective antagonist

✍ Scribed by Dechun Geng; Yaozeng Xu; Huilin Yang; Junhua Wang; Xuesong Zhu; Guangming Zhu; Xianbin Wang


Book ID
103827522
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
820 KB
Volume
31
Category
Article
ISSN
0142-9612

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## Abstract Wear particle‐induced osteoclastogenesis is the most common cause of aseptic loosening in total joint arthroplasty. Although cyclooxygenase (COX)‐2, an inducible regulator of prostaglandin E2 (PGE2) synthesis, is known to be involved in osteoclast differentiation, its effect on osteocla

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