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Protection against glutamate toxicity through inhibition of the p44/42 mitogen-activated protein kinase pathway in neuronally differentiated P19 cells

โœ Scribed by Elfrida R. Grant; Monica A. Errico; Stuart L. Emanuel; Daniel Benjamin; Michael K. McMillian; Scott A. Wadsworth; Robert A. Zivin; Zhong Zhong


Book ID
113992697
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
451 KB
Volume
62
Category
Article
ISSN
0006-2952

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Glial cell line-derived neurotrophic fac
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Glial cell line-derived neurotrophic factor (GDNF) promotes the survival or differentiation of several types of neurons. This study examines GDNF-induced signal transduction and biological effects in cultured striatal neurons. Results show that GDNF addition to striatal cultures transiently increase