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Protection against collagen-induced arthritis by electrotransfer of an expression plasmid for the interleukin-4

✍ Scribed by Seong-Hyun Ho; Woong Hahn; Hwang-Jae Lee; Dong-Sik Kim; Jae-Gyun Jeong; Sujeong Kim; Seung Shin Yu; Eun-Seok Jeon; Sunyoung Kim; Jong-Mook Kim

Book ID: 116288936
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 416 KB
Volume: 321
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2004.07.028

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## Abstract ## Objective Following the demonstration that the stress protein, BiP, prevented induction of collagen‐induced arthritis (CIA) in HLA–DRB\*0101^+/+^ (HLA–DR1^+/+^) mice, we investigated the immunotherapeutic ability of BiP to suppress disease during the active phase of CIA in HLA–DR1^+