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Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells

✍ Scribed by Alessio Nencioni; Anna Garuti; Karin Schwarzenberg; Gabriella Cirmena; Giovanna Dal Bello; Ilaria Rocco; Eleonora Barbieri; Peter Brossart; Franco Patrone; Alberto Ballestrero

Book ID: 118283381
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 324 KB
Volume: 36
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.200535298

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## Abstract Proteasome inhibitors are known to induce apoptosis in a variety of cancer cells. On the other hand, maspin, a non‐inhibitory serine protease inhibitor, is shown to sensitize cancer cells to therapeutic agents that induce apoptosis. We examined the consequence of maspin expression in pr