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Proteasome inhibition suppresses essential immune functions of human CD4+ T cells

โœ Scribed by Carsten Berges; Heinrich Haberstock; Dominik Fuchs; Marion Miltz; Mahmoud Sadeghi; Gerhard Opelz; Volker Daniel; Cord Naujokat

Book ID
108782249
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
487 KB
Volume
124
Category
Article
ISSN
0019-2805

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โœ Carsten Berges; Heinrich Haberstock; Dominik Fuchs; Mahmoud Sadeghi; Gerhard Ope ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 420 KB ๐Ÿ‘ 1 views

## Abstract We have previously shown that inhibition of the proteolytic activity of the proteasome induces apoptosis and suppresses essential functions of activated human CD4^+^ T cells, and we report now the detailed mechanisms of apoptosis following proteasome inhibition in these cells. Here we s