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Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells

✍ Scribed by Montserrat Caballero; Paloma B Liton; David L Epstein; Pedro Gonzalez


Book ID
117054400
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
242 KB
Volume
308
Category
Article
ISSN
0006-291X

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The trabecular meshwork (TM) is a specialized eye tissue that regulates the aqueous humor outflow and controls intraocular pressure. Cells in this tissue are essential for maintenance of the outflow system. Disturbance of the TM cell status by insults such as oxidative stress may lead to elevation o