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Proteasomal insensitivity of apoptin in tumor cells

✍ Scribed by Henriëtte L. Lanz; Johnny Suijker; Mathieu H.M. Noteborn; Claude Backendorf


Book ID
116303413
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
475 KB
Volume
422
Category
Article
ISSN
0006-291X

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## Abstract Chicken anemia virus viral protein 3 (VP3 or apoptin) localizes more efficiently in the nucleus of transformed than nontransformed cells. Although previous studies implicate the C‐terminus of apoptin as being responsible, the molecular basis is controversial, and the extent to which alt