A novel approach to screening phage-displayed peptide libraries has been used to identify hepatitis C virus (HCV) core, NS4 and NS5 sequences, which are antigenic in humans. Two random peptide libraries were used for screening using a mixture of HCV-positive sera or individual antibodies to core, NS
✦ LIBER ✦
Protease Site-Restricted Selection of Phage-Displayed Peptides on Glutathione–Sepharose
✍ Scribed by Taian Cui; Yalin Jiang; Alan G. Porter
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 70 KB
- Volume
- 244
- Category
- Article
- ISSN
- 0003-2697
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Molecular imprinting and phage display library technologies are rapidly being accepted as useful techniques for the generation of ligand-selective recognition motifs. The use of molecular imprinting to produce a novel type 11 aldolase mimic selective for the cobalt(I1)-mediated aldol condensation of