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Protease-activated receptors: novel PARtners in innate immunity

โœ Scribed by V. Shpacovitch; M. Feld; N.W. Bunnett; M. Steinhoff


Book ID
116577891
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
1018 KB
Volume
28
Category
Article
ISSN
1471-4906

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โœ Takeda, K. ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Oxford University Press ๐ŸŒ English โš– 989 KB

Functional characterization of Toll-like receptors (TLRs) has established that innate immunity is a skillful system that detects invasion of microbial pathogens. Recognition of microbial components by TLRs initiates signal transduction pathways, which triggers expression of genes. These gene product