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Protease-activated receptors and endothelial prostanoid production

✍ Scribed by Caroline P.D. Wheeler-Jones


Book ID
116983889
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
55 KB
Volume
40
Category
Article
ISSN
0022-2828

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## Abstract Protease‐activated receptors (PARs) are widely expressed within the heart. They are activated by a myriad of proteases, including coagulation proteases. __In vitro__ studies showed that activation of PAR‐1 and PAR‐2 on cardiomyocytes induced hypertrophy. In addition, PAR‐1 stimulation o