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Protease activated receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis

โœ Scribed by Soo-Jin Oh, Kyung-Seok Han, Hyungju Park, Dong ho Woo, Hye Yun Kim, Stephen F Traynelis, C Justin Lee


Book ID
119913516
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
924 KB
Volume
5
Category
Article
ISSN
1756-6606

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โœ Wei C. Chen; Ching-C. Chen ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 210 KB ๐Ÿ‘ 2 views

ATP-induced arachidonic acid (AA) release was studied in [ 3 H]AAprelabeled cultured astrocytes. To characterize the P 2 purinoceptor-mediated effect of ATP, the subtype-specific agonists 2-methylthio ATP (2-MeSATP) and UTP were compared. ATP, UTP, or 2-MeSATP induced a dose-dependent increase of [