Prostatropin and acidic FGF also support proliferation of an EGF-dependent keratinocyte cell line

Comparison of the ability of basic and a

Comparison of the ability of basic and acidic fibroblast growth factor to stimulate the proliferation of an established keratinocyte cell line: Modulation of their biological effects by heparin, transforming growth factor β (TGFβ), and epidermal growth factor (EGF)

✍ D. Gospodarowicz; J. Plouët; B. Malerstein 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 910 KB

## Abstract The bioactivity of both bFGF and aFGF in the BALB/MK‐1 cell line has been compared to that of EGF. Our results indicate that, for that cell type, aFGF was far more potent than bFGF in inducing cell proliferation. In the presence of heparin, aFGF was as potent as EGF. In addition, excess