Prostatic Intraepithelial Neoplasia and Apoptosis in Benign Prostatic Hyperplasia Before and After the Chernobyl Accident in Ukraine
✍ Scribed by Alexander F Vosianov; Alina M Romanenko; Larisa B Zabarko; Béla Szende; Ching Y Wang; Steven Landas; Gabriel P Haas
- Book ID
- 111723850
- Publisher
- Springer Netherlands
- Year
- 1999
- Tongue
- English
- Weight
- 95 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1219-4956
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## Background: High grade prostatic intraepithelial neoplasia (pin) is associated with coincident prostate carcinoma, and has been considered to be a precursor of prostate carcinoma. most studies on pin have been performed on total prostatectomy or core needle biopsy specimens. few reports deal wit
BACKGROUND. Imbalance between cell proliferation and cell apoptosis has been considered a key factor in carcinogenesis. Prostatic intraepithelial neoplasia (PIN) is the most likely precancereous lesion and represents the major target for chemoprevention of prostate cancer. The proliferative and apop