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Prostate tumor-initiating cells: A new target for telomerase inhibition therapy?

✍ Scribed by Calin O. Marian; Jerry W. Shay

Book ID: 116270760
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 476 KB
Volume: 1792
Category: Article
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2009.02.012

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## Abstract There is growing evidence to suggest that not all cancer cells have similar levels of malignant potential and that tumor progression may be driven by specialized sub‐sets of “tumor initiating” cells. It is likely that as tumor initiating cells have lower proliferation rates and enhanced