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Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies

โœ Scribed by K.T. Christov; R.C. Moon; D.D. Lantvit; C.W. Boone; G.J. Kelloff; V.E. Steele; R.A. Lubet; J.M. Pezzuto


Book ID
116428075
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
400 KB
Volume
40
Category
Article
ISSN
0959-8049

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## BACKGROUND. In an effort to identify biomarker(s) for prostatic cancer (PCa), we analyzed the changes of secretory proteins in the ventral prostate (VP) of Noble rats at early stages of carcinogenesis. METHODS. Ventral prostates were removed from both control (n = 36) and experimental (n = 88) r