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Prostate III—A structural feature characteristic of the rat prostate 5α-reductase active site

✍ Scribed by Vladimir Petrow; George M. Padilla; Andrew T. McPhail; Nicholas Bruchovsky; Sara L. Schneider

Book ID
116007487
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
871 KB
Volume
32
Category
Article
ISSN
0022-4731

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BACKGROUND. Turosteride (FCE 26073) is a new, potent, and selective 5␣-reductase inhibitor. We have investigated its effect on tumor growth, organ weight, and serum hormone levels in rats bearing the androgen sensitive Dunning R3327 prostatic carcinoma. METHODS. Animals with tumor diameters of 0.5-1