Prostate Biopsy Interpretation: An Illustrated Guide

✍ Scribed by Rajal B. Shah, Ming Zhou (auth.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 2012
• Tongue: English
• Leaves: 202
• Edition: 1
• Category: Library

✦ Synopsis

This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of “atypical” diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. Algorithms, flow charts, and tables are used throughout to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. The book is richly illustrated with carefully selected, high-quality color images and will appeal especially to practicing surgical pathologists as well as pathology residents and fellows in training.

✦ Table of Contents

Front Matter....Pages i-xvi
Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Practice....Pages 1-10
Prostate Needle Biopsy Sampling Techniques: Impact on Pathological Diagnosis....Pages 11-14
Diagnosis of Limited Cancer in Prostate Biopsy....Pages 15-27
Immunohistochemistry in Prostate Biopsy Evaluation....Pages 29-40
Contemporary Approach to Gleason Grading of Prostate Cancer....Pages 41-55
Histologic Variants of Prostate Carcinoma....Pages 57-78
Benign Mimics of Prostate Carcinoma....Pages 79-113
Atypical Cribriform Lesions of the Prostate Gland: Emerging Concepts of Intraductal Carcinoma of the Prostate (IDC-P)....Pages 115-120
High-Grade Prostatic Intraepithelial Neoplasia....Pages 121-130
Atypical Glands Suspicious for Cancer....Pages 131-138
Spindle Cell Lesions of the Prostate Gland....Pages 139-145
Treatment Effect in Benign and Malignant Prostate Tissue....Pages 147-155
Molecular Biology of Prostate Cancer and Emerging Diagnostic and Prognostic Biomarkers....Pages 157-167
Biopsy Specimen Handling, Processing, Quality Assurance Program....Pages 169-172
Reporting of Prostate Biopsy....Pages 173-180
Back Matter....Pages 181-185

✦ Subjects

Pathology; Urology/Andrology