Background. Vascular endothelial growth factor (VEGF) is a specific endothelial cell mitogen that stimulates angiogenesis and plays a crucial role in tumor growth. The aim of the present study was to evaluate the expression of VEGF and of its two high-affinity tyrosine kinase receptors (KDR and Flt-
β¦ LIBER β¦
PROSTANOID-MEDIATED SIGNALLING IN ENDOTHELIUM AND OSTEOBLASTS: EFFECTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) AND VEGF RECEPTOR (VEGFR) BLOCKADE
β Scribed by Claire E Clarkin; Andrew A Pitsillides; Caroline PD Wheeler-Jones
- Book ID
- 116341975
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 41 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1054-8807
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## Abstract Angiogenesis, the formation of new blood vessels, is controlled by a balance between positive and negative endothelial regulatory factors. Soluble vascular endothelial growth factor receptorβ1 (sVEGFR1), a naturally occurring soluble form of VEGFR1, is a negative counterpart of the vasc