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Prostanoid formation in primary astroglial cell cultures: Ca2+-dependency and stimulation by A 23187, melittin and phospholipases A2 and C

✍ Scribed by Keller, Manfred; Seregi, Andras; Hertting, Georg; Jackisch, Rolf

Book ID
123054487
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
818 KB
Volume
10
Category
Article
ISSN
0197-0186

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Melittin, a peptide from bee venom, is thought to be a phospholipase A(2) activator and Ca(2+) influx inducer that can evoke cell death in different cell types. However, the effect of melittin on cytosolic free Ca(2+) concentration ([Ca(2+)](i)) and viability has not been explored in human osteoblas