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Prostaglandins of the E series inhibit cytokine-induced metalloprotease expression through a cAMP-dependent signaling pathway in human synovial fibroblasts


Book ID
114348731
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
111 KB
Volume
1
Category
Article
ISSN
1063-4584

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## Objective: To investigate the effects of the antiinflammatory cytokines interleukin-4 (il-4), il-10, and il-13 on tumor necrosis factor alpha (tnfalpha)-induced prostaglandin e2 (pge2) release in the cellular signaling cascade on human osteoarthritis (oa) synovial fibroblasts. ## Methods: Huma