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Prostaglandin-releasing effect of exogenous noradrenaline in isolated rabbit heart

✍ Scribed by Pham-Huu-Chanh; M. C. Nicot-Carthéry

Publisher
Springer
Year
1973
Tongue
English
Weight
203 KB
Volume
60
Category
Article
ISSN
0028-1042

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Endothelin (ET-1) is found at elevated concentrations in the plasma of patients with heart failure and in animal models of cardiomyopathy. The peptide is a potent positive inotropic agent, the effects of which are mediated by increases in cytosolic Ca2+ in cardiomyocytes. The object of this study wa