PGE2 receptor EP1 renders dopaminergic n
โ
Emilce Carrasco; Diana Casper; Peter Werner
๐
Article
๐
2007
๐
John Wiley and Sons
๐
English
โ 273 KB
๐ 1 views
Oxidative stress and increased cyclooxygenase-2 (COX-2) activity are both implicated in the loss of dopaminergic neurons from the substantia nigra (SN) in idiopathic Parkinson's disease (PD). Prostaglandin E 2 (PGE 2 ) is one of the key products of COX-2 activity and PGE 2 production is increased in