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Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception

✍ Scribed by Yingqi Weng, Patricia A Batista-Schepman, Marie E Barabas, Eli Q Harris…


Book ID
120694718
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
633 KB
Volume
8
Category
Article
ISSN
1744-8069

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## Abstract TRPA1 and TRPM8 are transient receptor potential (TRP) channels involved in sensory perception. TRPA1 is a non‐selective calcium permeable channel activated by irritants and proalgesic agents. TRPM8 reacts to chemical cooling agents such as menthol. The human neuroblastoma cell line IMR