Expression of microsomal prostaglandin E
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Bastiaan P. van Rees; Anna Sivula; Staffan ThorΓ©n; Hiroshi Yokozaki; Per-Johan J
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Article
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2003
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John Wiley and Sons
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French
β 317 KB
Gastrointestinal carcinomas synthesize elevated levels of prostaglandin E(2) (PGE(2)), which has been mechanistically linked to carcinogenesis. Recently, microsomal prostaglandin E synthase-1 (mPGES-1) was cloned, which seems to be inducible and linked to cyclooxygenase-2 (Cox-2) in the biosynthesis