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Prostaglandin endoperoxide synthetase-mediated metabolism of carcinogenic aromatic amines and their binding to DNA and protein

✍ Scribed by F.F. Kadlubar; C.B. Frederick; C.C. Weis; T.V. Zenser


Book ID
115756116
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
349 KB
Volume
108
Category
Article
ISSN
0006-291X

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Cytochrome P4501A2 constitutively expres
✍ Narayana Battula; Herman A. J. Schut; Snorri S. Thorgeirsson πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 718 KB

We transduced mouse cytochrome P4501A2 DNA into NIH 3T3 cells by retrovirus-mediated gene transfer. The capacity of the transduced cytochrome P4501A2 for metabolic activation and DNA-carcinogen adduct formation of aromatic amine carcinogens was investigated. Clones of NIH 3T3 cells that constitutive