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Prostaglandin E2 production in ovarian cancer cell lines is regulated by cyclooxygenase-1, not cyclooxygenase-2

✍ Scribed by Yuko Kino; Fumiaki Kojima; Kazushige Kiguchi; Rie Igarashi; Bunpei Ishizuka; Shinichi Kawai

Book ID
116838390
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
419 KB
Volume
73
Category
Article
ISSN
0952-3278

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## Abstract Augmented expression of protein kinase CK2 is associated with hyperproliferation and resistance to apoptosis in cancer cells. Effects of CK2 are at least partially linked to signaling via the Wnt/β‐catenin pathway, which is dramatically enhanced in colon cancer. Cyclooxygenase‐2 (COX‐2)