Prostaglandin E2 inhibition of sodium transport in the freshwater mussel

✍ Scribed by Graves, Sidney Yeider ;Dietz, Thomas H.

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 265 KB
• Volume: 210
• Category: Article
• ISSN: 0022-104X
• DOI: 10.1002/jez.1402100123

✦ Synopsis

Abstract

Ligumia subrostrata (Say) will maintain a steady state for Na when acclimated to an artificial pondwater. Prostaglandin E^2^ (0.6 μM/g dry tissue) injected into the blood cause an 80% reduction of Na influx and the animals experience a net loss of Na. Injections of indomethacin (0.1 μM/g dry tissue), a prostaglandin synthetase inhibitor, cause a doubling of Na influx relative to control animals. Prostaglandin‐like material can be extracted from the blood of L. subrostrata and may be a component of the endocrine control of ion regulation in freshwater bivalves.