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Prostaglandin E2-dependent IL-23 production in aged murine dendritic cells

✍ Scribed by Rebecca G. Myer; Rabab El Mezayen; Kevin P. High

Book ID
113615400
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
936 KB
Volume
45
Category
Article
ISSN
0531-5565

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Prostaglandin (PG) D(2), and its metabolites, are known to be important mediators during acute and chronic inflammation. However, their functions during the early phases of the immune response are poorly documented. In the present study, we show that PGD(2 )inhibits, in a dose-dependent manner, the