Prostaglandin E2 and prostaglandin F2α involvement in the corticosterone and cortisol release by the female frog,Rana esculenta, during ovulation

✍ Scribed by Gobbetti, Anna ;Zerani, Massimo

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 713 KB
• Volume: 267
• Category: Article
• ISSN: 0022-104X
• DOI: 10.1002/jez.1402670209

✦ Synopsis

Abstract

Interrenal and ovarian tissues of Rana esculenta were incubated in vitro during the preovulatory, ovulatory and postovulatory phases to study the basal release of prostaglandin E~2~ (PGE~2~), prostaglandin F~2α~, (PGF~2α~), corticosterone, and cortisol. The effects of exogenous PGE~2~ and PGF~2α~ on interrenal and ovarian corticosteroid release were also studied. In addition, the plasma values of these four hormones were assessed during the same phases. During in vitro interrenal incubations, PGE~2α~ PGF~2α~, corticosterone, and cortisol basal releases were higher in the postovulatory phase, PGE~2~, and PGF~2α~ treatment in vitro increased corticosteroids during the ovulatory phase. During in vitro ovarian incubations, PGE~2~ basal release was higher in the preovulatory phase and PGF~2α~ and corticosteroids in the ovulatory phase; PGE~2~ treatment in vitro decreased corticosteroids in the ovulatory phase, and PGF~2α~ increased corticosteroids in the preovulatory and postovulatory phases. PGE~2~, corticosterone and cortisol plasma values were higher during the postovulatory phase, while PGF~2α~, was elevated during the ovulatory phase. These findings suggest that ovarian corticosteroids could be considered one of the factors inducing ovulation and that their synthesis may be modified by PGs. © 1993 Wiley‐Liss, Inc.