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Prostaglandin E1 and misoprostol increase epidermal growth factor production in 3D-cultured human annulus cells

✍ Scribed by Helen E. Gruber; Gretchen Hoelscher; Bryan Loeffler; Yin Chow; Jane A. Ingram; Will Halligan; Edward N. Hanley Jr.


Book ID
119371436
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
280 KB
Volume
9
Category
Article
ISSN
1529-9430

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## Abstract Heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) has been shown to be a potent smooth muscle cell (SMC) mitogen and chemoattractant, and might be a candidate factor for the progression of atherosclerosis. We have investigated the effects of high glucose and hyperosmol