Prostaglandin-dependent activation of ERK mediates cell proliferation induced by transforming growth factor β in mouse osteoblastic cells
✍ Scribed by Chafik Ghayor; Alexandre Rey; Joseph Caverzasio
- Book ID
- 116319078
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 416 KB
- Volume
- 36
- Category
- Article
- ISSN
- 8756-3282
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## Abstract Osteoblasts secrete transforming growth factor beta (TGFβ) as a biologically inert, latent complex that must be dissociated before the growth factor can exert its effects. We have examined the production and proteolytic activation of latent TGFβ (LTGFβ) by clonal UMR 106‐01 rat osteosar