Prospects for the development of validated screening tests that measure developmental toxicity potential: View of one skeptic

✍ Scribed by Mirkes, Philip E.

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 540 KB
• Volume: 53
• Category: Article
• ISSN: 0040-3709
• DOI: 10.1002/(sici)1096-9926(199606)53:6<334::aid-tera3>3.0.co;2-#

✦ Synopsis

Humans are exposed to a variety of potential developmental toxicants. This fact, combined with the knowledge that human development can be disrupted by "environmental" agents, has led to the development of methods designed to identify potential developmental toxicants. Currently, the principal method used to screen drugs and chemicals that are potential human developmental toxicants is the segment ll study (i.e., a study in which prospective drugs and