Swern oxidation of chromanol 1 led to ketone 3 with concomitant chlorination of the adjacent 4-position. Using Leuckarl conditions, chromanone 2 was converted to enamine 5. -4-Bromochromene-3-carbaldehyde 8, which was obtained by Vilsmeier-Arnold reaction from 7, turned out to be a suitable intermed
Prospects for Potassium Channel Activators in the Treatment of Airways Obstruction
β Scribed by D.R. Buckle
- Publisher
- Elsevier
- Year
- 1993
- Tongue
- English
- Weight
- 510 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0952-0600
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