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Prospective Validation of High-Shear Wet Granulation Process by Wet Granule Sieving Method. II. Utility of Wet Granule Sieving Method

โœ Scribed by Emori, Hisatoshi; Sakuraba, Yoko; Takahashi, Koji; Nishihata, Toshiaki; Mayumi, Tadanori


Book ID
120559831
Publisher
Informa plc
Year
1997
Tongue
English
Weight
791 KB
Volume
23
Category
Article
ISSN
0363-9045

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The objective is to provide mechanistic understanding of a preferred wet granulation process that a binder is added in a dry state. Blends of CaCO(3) and binders were prepared and used as model systems, and they were exposed to either 96% RH (rubbery/solution state) or 60% RH (glassy state) at room