Prospective research on the efficacy and safety of oxcarbazepine as monotherapy and add-on therapy for partial epilepsy
โ Scribed by Kang, Huicong ;Liu, Xiaoyan ;Qi, Hu ;Xu, Feng ;Li, Xiang ;Wang, Yuan ;Liu, Zhiguang ;Zhu, Suiqiang
- Book ID
- 107472292
- Publisher
- Higher Education Press and Springer
- Year
- 2009
- Tongue
- English
- Weight
- 111 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1673-7342
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Thirteen drug-resistant epilepsy patients received loreclezole as add-on therapy. The trial lasted 6 months. Loreclezole was dosed to reach a target plasma concentration between 1 and 3 mg/l. The seizure frequency in the total group decreased by 23%. A reduction of 50% or more was observed in four p
Sixty-two patients with uncontrolled partial seizures participated in a 12-week, double-blind, placebo-controlled add-on-trial. Thirty-two patients received loreclezole and 30 a placebo as add-on therapy. Loreclezole was targeted at a plasma level of 1-2 mg/l. In spite of an antiepileptic therapy, u