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Prospective randomized study of selective neck dissection versus observation for N0 neck of early tongue carcinoma

✍ Scribed by Anthony Po-Wing Yuen; Chiu Ming Ho; Tam Lin Chow; Lap Chiu Tang; Wing Yung Cheung; Raymond Wai-Man Ng; William Ignace Wei; Chi Kwan Kong; Kwok Shing Book; Wai Cheung Yuen; Alfred King-Yin Lam; Nancy Wah-Fun Yuen; Nigel Jeremy Trendell-Smith; Yue Wai Chan; Birgitta Yee-Hang Wong; George Kam-Hop Li; Ambrose Chung-Wai Ho; Wai Kuen Ho; Sau Yan Wong; Tzy-Jyun Yao

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 100 KB
Volume: 31
Category: Article
ISSN: 1043-3074
DOI: 10.1002/hed.21033

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background.

There are controversies on the benefits of elective neck dissection (END) for oral tongue carcinoma.

Method.

This is a prospective randomized study of elective selective I, II, III neck dissection versus observation for N0 neck of stage I to II oral tongue carcinoma. There were 35 patients on the observation arm and 36 patients on the END arm. The main outcome assessment parameters are node‐related mortality and disease‐specific survival rate.

Results.

There were 11 patients in the observed arm and 2 patients in the END arm who developed nodal recurrence alone without associated local or distant recurrence. All 13 patients were salvaged, and no patient died of nodal recurrence. The 5‐year disease‐specific survival rate was 87% for the observation arm and was 89% for the END arm; the 2% difference was not significant.

Conclusion.

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