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Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis

✍ Scribed by Mishra, Jayshree; Drummond, Joseph; Quazi, Sohel H.; Karanki, Satya Sridhar; Shaw, J.J.; Chen, Ben; Kumar, Narendra


Book ID
119957330
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
880 KB
Volume
86
Category
Article
ISSN
1040-8428

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## Abstract Activation of the epidermal growth factor receptor (EGFR) contributes to the pathogenesis of non‐small‐cell lung carcinomas (NSCLC) and gefitinib, a selective reversible EGFR inhibitor, is effective in treating patients with NSCLC. However, clinical resistance to gefitinib is a frequent