Combinatorial treatment of non-small-cel
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Luni Emdad; Irina V. Lebedeva; Zao-Zhong Su; Pankaj Gupta; Devanand Sarkar; Jeff
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Article
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2006
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John Wiley and Sons
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English
β 497 KB
## Abstract Activation of the epidermal growth factor receptor (EGFR) contributes to the pathogenesis of nonβsmallβcell lung carcinomas (NSCLC) and gefitinib, a selective reversible EGFR inhibitor, is effective in treating patients with NSCLC. However, clinical resistance to gefitinib is a frequent