Diffusion tensor imaging is unique in its ability to noninvasively visualize white matter fiber tracts in the human brain in vivo. Diffusion is the incoherent motion of water molecules on a microscopic scale. This motion is itself dependent on the micro-structural environment that restricts the move
Propriospinal myoclonus: Utility of magnetic resonance diffusion tensor imaging and fiber tracking
✍ Scribed by Emmanuel Roze; Emmanuelle Apartis; Marie Vidailhet; Valérie Cochen; Yara Beaugendre; Jean-Marc Trocello; Pierre Lasjaunias; Denis Ducreux
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 151 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0885-3185
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✦ Synopsis
Abstract
Propriospinal myoclonus (PSM) is a rare movement disorder characterized by involuntary spinal‐generated muscular jerks that spread rostrally and caudally to other spinally innervated muscles. Most patients have no clear etiology, and conventional MRI of the spinal cord is generally normal. Here we report the use of magnetic resonance diffusion tensor imaging (DTI) and fiber tracking to detect tract‐specific abnormalities in a patient with propriospinal myoclonus. As the patient had the fragile‐X premutation and antithyroid antibodies, spinal cord DTI abnormalities may be related to these conditions. Tract‐specific analysis may provide new insights into the pathophysiology of propriospinal myoclonus. © 2007 Movement Disorder Society
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