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Propriospinal myoclonus: Utility of magnetic resonance diffusion tensor imaging and fiber tracking

✍ Scribed by Emmanuel Roze; Emmanuelle Apartis; Marie Vidailhet; Valérie Cochen; Yara Beaugendre; Jean-Marc Trocello; Pierre Lasjaunias; Denis Ducreux


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
151 KB
Volume
22
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

Propriospinal myoclonus (PSM) is a rare movement disorder characterized by involuntary spinal‐generated muscular jerks that spread rostrally and caudally to other spinally innervated muscles. Most patients have no clear etiology, and conventional MRI of the spinal cord is generally normal. Here we report the use of magnetic resonance diffusion tensor imaging (DTI) and fiber tracking to detect tract‐specific abnormalities in a patient with propriospinal myoclonus. As the patient had the fragile‐X premutation and antithyroid antibodies, spinal cord DTI abnormalities may be related to these conditions. Tract‐specific analysis may provide new insights into the pathophysiology of propriospinal myoclonus. © 2007 Movement Disorder Society


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