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Propriospinal myoclonus after treatment with ciprofloxacin

✍ Scribed by Bart Post; Johannes H.T.M. Koelman; Marina A.J. Tijssen

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
514 KB
Volume
19
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

The clinical and electrophysiological features of a truncal myoclonus in a 55‐year‐old man are described. The electromyographic characteristics point toward propriospinal myoclonus. It is suggested that a myoclonic generator was released after use of ciprofloxacin, by antagonising the γ‐aminobutyric acid metabolism. Β© 2004 Movement Disorder Society

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## Abstract We report on a man who received interferon‐α 2a therapy for kidney cancer and who subsequently developed propriospinal myoclonus. The myoclonus was noted at rest and during movement. The jerks were reinforced by cutaneous stimuli and tendon taps and spread to the spinal cord via polysyn