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Propranolol toxicity and the use of intravenous glucagon in the dog model

โœ Scribed by L Hartnett; W Longmore; MA Howland


Book ID
104313310
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
150 KB
Volume
14
Category
Article
ISSN
1097-6760

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Conscious male Wistar SPF Riv:TOX rats were dosed intravenously with 2.5, 5, or 10 mg/kg rac-propranolol.HCl, or with 5 mg/kg of either (-)-(S)- or (+)-(R)-propranolol.HCl. Disposition of (-)-(S)- and (+)-(R)-propranolol after dosing of rac-propranolol was linear in the dose range examined. Total pl