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Propranolol in the prophylaxis of oesophageal variceal haemorrhage in patients with cirrhosis: A double-blind, multicenter controlled trial

✍ Scribed by Bosch, J; Groszmann, RJ; Grace, N; Navasa, M; Conn, HO; Rodés, J

Book ID
123051018
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
73 KB
Volume
10
Category
Article
ISSN
0168-8278

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Propranolol for prophylaxis of bleeding in cirrhotic patients with large varices: A multicenter, randomized clinical trial
📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB 👁 2 views

To assess if propranolol prevents the first bleeding in cirrhosis, we randomly assigned 174 patients with large varices to either propranolol in doses reducing the resting heart rate by 25% (85 patients) or to a placebo (oral vitamin K, 89 patients). Sixty-nine patients had alcoholic cirrhosis, 24 p