Propranolol and endoscopic sclerosis of esophageal varices are the two approaches currently used in prophylaxis of the first gastrointestinal hemorrhage in the cirrhotic patient. One hundred twenty-six cirrhotic patients with esophageal varices and no histories of bleeding were included in the trial
Propranolol in the prevention of recurrent upper gastrointestinal bleeding in patients with cirrhosis undergoing endoscopic sclerotherapy. A randomized controlled trial
β Scribed by Alec Avgerinos; George Rekoumis; Chrisostomos Klonis; Nickos Papadimitriou; Paraskevi Gouma; Stavros Pournaras; Sotos Raptis
- Book ID
- 117990664
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 819 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0168-8278
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π SIMILAR VOLUMES
We have previously reported the results of a controlled trial showing that continuous oral administration of propranolol reduced the risk of recurrent gastrointestinal bleeding in patients with cirrhosis; only part of our patients had been followed for 1 year. This controlled trial was continued for
To assess the efficacy of &blockers in preventing rebleeding in selected cirrhotic patients and to compare the tolerance, safety and patient compliance of a selective and a nonselective @-blocker, 9 4 patients were randomly assigned to propranolol (32 patients), atenolol (32 patients) or placebo (30
We conducted a prospective, multicenter, randomized trial to compare the efficacy of sclerotherapy plus propranolol with that of propranolol alone in the prevention of recurrent gastroesophageal bleeding in severely cirrhotic patients. For 2 yr (1987 to 1988) 131 patients (96% of whom were alcoholic
In a previous randomized trial, we demonstrated that propranolol prevented recurrent gastrointestinal bleeding in patients with cirrhosis. We have undertaken the present study in a new group of patients to ascertain the factors associated with rebleeding. Among 232 patients with cirrhosis admitted f