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(-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists

✍ Scribed by Jeffery S. Sprouse; George K. Aghajanian


Book ID
115880425
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
320 KB
Volume
128
Category
Article
ISSN
0014-2999

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Previous studies [Meller et al. (1990) Mol. Pharmacol., 37:231-2371 have shown that a large receptor reserve exists for the inhibition of serotonin synthesis in rat cortex and hippocampus by the 5-HTlA agonist 8-hydroxy-2(di-n-propylamino)tetralin (gOH-DPAT), whereas little or no reserve exists for