Proposed role for the α2 chain in resolving an ambiguity in self — Assembly of the collagen fibril
✍ Scribed by David W.L. Hukins; John Woodhead-Galloway
- Book ID
- 118311125
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 234 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Procollagen (Type I) contains a noncollagenous COOH-terminal propeptide (C-propeptide) hypothesized to be important in directing chain association and alignment during assembly. We previously expressed human pro-␣2(I) cDNA in rat liver epithelial cells, W8, that produce only pro-␣1(I) trimer collage
Collagen biosynthesis is a complex process that begins with the association of three procollagen chains. A series of conserved intra-and interchain disulfide bonds in the carboxyl-terminal region of the procollagen chains, or C-propeptide, has been hypothesized to play an important role in the nucle