Proposal for a scoring of the quality of the banding of chromosomes
β Scribed by J. L. Huret; C. Leonard; A. Aurias
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 810 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
β¦ Synopsis
We propose an objective scoring of the quality of the banding of mitoses based on the number of bands (B), the length (L), and the width (W) of chromosome 7 in metaphase as used in the formula [LnB square root L/W]2. When no figure shows the quality of mitoses from which a breakpoint is described, this scoring could give information about it. It could be applied in cytogenetic cancer studies as well as for preparations with high resolution banding.
π SIMILAR VOLUMES
The role of trypsin in the elicitation of G-banding on human chromosomes was studied in two separate laboratories. Enzyme activity and ability of trypsin to chelate calcium were manipulated by dilution of the treatment solution, and by inhibition with diisopropylphosphofluoridate, diphenylcarbamyl c
Q and G banding studies of the chromosomes of a specimen of Lagothrix lagothricha cana permitted identification of a// pairs in the complement. The X is a medium-sized submetacentric, the Y a very small acrocentric. Some chromosome pairs show banding patterns identical to those found in some chromos