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Propolis protects human spermatozoa from DNA damage caused by benzo[a]pyrene and exogenous reactive oxygen species

โœ Scribed by A. Russo; N. Troncoso; F. Sanchez; J.A. Garbarino; A. Vanella


Book ID
116717833
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
131 KB
Volume
78
Category
Article
ISSN
0024-3205

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Benzo[a]pyrene (BaP) is an agonistic ligand for the aryl hydrocarbon receptor (AhR) and a major environmental carcinogen implicated in the aetiology of lung cancer through the induction of benzo[a]pyrene diol epoxidation (BPDE) and BPDE-DNA adducts. Because BaP metabolization requires cytochrome P-4