Nrf2 is increased by CYP2E1 in rodent li
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Pengfei Gong; Arthur I. Cederbaum
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Article
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2006
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John Wiley and Sons
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English
โ 259 KB
Induction of CYP2E1 by ethanol is one pathway through which ethanol generates oxidative stress. Nrf2 is a transcription factor that regulates important antioxidant and phase II detoxification genes. Nrf2 induction by CYP2E1 and its importance in the adaptive response to increased oxidative stress ca