Investigating the role of native propion
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Haoran Zhang; Brett A. Boghigian; Blaine A. Pfeifer
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Article
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2010
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John Wiley and Sons
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English
⚖ 475 KB
👁 1 views
## Abstract 6‐Deoxyerythronolide B (6dEB) is the macrocyclic aglycone precursor of the antibiotic natural product erythromycin. Heterologous production of 6dEB in __Escherichia coli__ was accomplished, in part, by designed over‐expression of a native __prpE__ gene (encoding a propionyl‐CoA syntheta